TRODELVY dose of 10 mg/kg is given as an intravenous (IV) infusion
Doses are given once a week for 2 weeks (Day 1 and Day 8) of 21-day treatment cycles
Each treatment cycle is 21 days (3 weeks)
Treatment cycles repeat every 21 days
You and your healthcare provider will decide how many treatment cycles you receive. This may be based on factors such as whether your tumor has responded to treatment or your body’s ability to tolerate treatment.
Before starting TRODELVY, tell your healthcare provider about any medicines you are taking. Be sure to include prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines may affect the way TRODELVY works.
After each infusion, your healthcare team will watch you for reactions for at least 30 minutes. If you experience any side effects while taking TRODELVY, tell your healthcare provider right away. Please read the Important Safety Information below and the information on Side Effects.
Your healthcare provider may give you medicines to take home that can help you manage possible side effects of TRODELVY. Keep track of when and how often side effects occur, as well as their severity, so your healthcare provider can best support you. Call your healthcare provider right away if you experience any side effects. Please review these Important Facts for more information.
Be sure to tell your healthcare team about any side effects you have while on TRODELVY.
TRODELVY® (sacituzumab govitecan-hziy) is a prescription medicine used to treat adults with:
It is not known if TRODELVY is safe and effective in people with moderate or severe liver problems or in children.
Do not receive TRODELVY if you have had a severe allergic reaction to TRODELVY. Ask your healthcare provider if you are not sure.
Allergic and infusion-related reactions which can be serious and life-threatening. Tell your healthcare provider or nurse right away if you get any of the following symptoms during your infusion of TRODELVY or within 24 hours after: swelling of your face, lips, tongue, or throat; hives; skin rash, itching, or flushing of your skin; fever; difficulty breathing or wheezing; lightheadedness, dizziness, feeling faint, or pass out; or chills or shaking chills (rigors).
Nausea and vomiting are common with TRODELVY and can sometimes be severe. Before each dose of TRODELVY, you will receive medicines to help prevent nausea and vomiting along with medicines to take home with instructions about how to take them. Call your healthcare provider right away if you have nausea or vomiting that is not controlled with the medicines prescribed for you. Your healthcare provider may decide to decrease your dose or stop TRODELVY if your nausea and vomiting is severe and cannot be controlled with anti-nausea medicines.
Before receiving TRODELVY, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines may affect the way TRODELVY works.
The most common side effects of TRODELVY include decreased white blood cell (leukocyte and lymphocyte) and red blood cell counts, feeling tired or weak, hair loss, constipation, increased sugar levels in the blood, decreased protein levels (albumin) in the blood, decreased appetite, changes in kidney function test, increased levels of enzyme called alkaline phosphatase in the blood (test for liver or bone problems), and decreased levels of magnesium, potassium, and sodium in the blood.
These are not all of the possible side effects of TRODELVY. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Please click to see Important Facts about TRODELVY, including Important Warning.